Article

Genome-Wide Association for Itraconazole Sensitivity in Non-Resistant Clinical Isolates of <i>Aspergillus fumigatus</i>

2020-08-31

Abstract excerpt

Aspergillus fumigatus is a potentially lethal opportunistic pathogen that infects over ∼200,000 people and causes ∼100,000 deaths per year globally. Treating A. fumigatus infections is particularly challenging because of the recent emergence of azole-resistance. The majority of studies focusing on the molecular mechanisms underlying azole resistance have examined azole-resistant isolates. However, isolates that a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ce60937e-6887-538e-93e5-9c967b20023f
DOI: 10.1101/2020.08.31.275297

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genome-Wide Association for Itraconazole Sensitivity in Non-Resistant Clinical Isolates of <i>Aspergillus fumigatus</i>DOI 10.1101/2020.08.31.275297Read

Genome-Wide Association for Itraconazole Sensitivity in Non-resistant Clinical Isolates of Aspergillus fumigatusSemantic proximity Read

Recreation of in-host acquired single nucleotide polymorphisms by CRISPR-Cas9 reveals an uncharacterised gene playing a role in Aspergillus fumigatus azole resistance via a non-cyp51A mediated resistance mechanismSemantic proximity Read

Genomic diversity of the pathogenic fungus Aspergillus fumigatus in Japan reveals the complex genomic basis of azole resistanceSemantic proximity Read

Pan-azole- and multi-fungicide-resistant <i>Aspergillus fumigatus</i> is widespread in the United StatesSemantic proximity Read

Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome Sequencing.Semantic proximity Read

Genome-Wide Association Analysis for Triazole Resistance in Aspergillus fumigatusSemantic proximity Read

Epidemiological and Genomic Landscape of Azole Resistance Mechanisms in Aspergillus FungiSemantic proximity Read

Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environmentSemantic proximity Read

Genomic Diversity of Azole-Resistant Aspergillus fumigatus in the United States.Semantic proximity Read

Whole-genome comparison of Aspergillus fumigatus strains serially isolated from patients with aspergillosis.Semantic proximity Read

Whole genome sequencing of newly emerged fungal pathogen <i>Aspergillus lentulus</i> and its Azole resistance gene predictionSemantic proximity Read

Tracing patterns of evolution and acquisition of drug resistant <i>Aspergillus fumigatus</i> infection from the environment using population genomicsSemantic proximity Read