Article

Aneuploidy, polyploidy, and loss of heterozygosity distinguish serial bloodstream isolates of <i>Candida albicans</i>

2025-10-27

Abstract excerpt

<h4>Background</h4> The opportunistic pathogen Candida albicans is the leading species causing invasive Candida infections worldwide. Genomic variation is widespread in clinical isolates and complicates identification of genetic variants underlying antifungal drug resistance and tolerance. Our understanding of genomic and phenotypic diversity during invasive infections is limited and studies of serial isolates...

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Literature Corpus work: 9534531b-f24f-525a-aa54-76d951e611d0
DOI: 10.1101/2025.10.27.684856

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