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Elevated mutation rates in the multi-azole resistant <i>Aspergillus fumigatus</i> clade drives rapid evolution of antifungal resistance

2023-12-05

Abstract excerpt

The evolution of antifungal resistance is an emerging global threat. Particularly concerning is the widespread occurrence of azole resistance within Aspergillus fumigatus , a globally ubiquitous environmental mould that causes over 1 million life-threatening invasive infections in humans each year. It is increasingly evident that the environmental use of azoles has led to selective sweeps across multiple genomic...

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Literature Corpus work
8867b56c-2cf8-5c33-80ee-3f5bcbd72d31
DOI
10.1101/2023.12.05.570068
Open publication

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Elevated mutation rates in the multi-azole resistant <i>Aspergillus fumigatus</i> clade drives rapid evolution of antifungal resistanceDOI 10.1101/2023.12.05.570068
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