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Detecting Azole-Antifungal Resistance in Aspergillus fumigatus by Pyrosequencing

10 Jan 2020

Abstract excerpt

Guidelines on the diagnosis and management of Aspergillus disease recommend a multi-test approach including CT scans, culture, fungal biomarker tests, microscopy and fungal PCR. The first-line treatment of confirmed invasive aspergillosis (IA) consists of drugs in the azole family; however, the emergence of azole-resistant isolates has negatively impacted the management of IA. Failure to detect azole-resistance...

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PMID: 31936898
DOI: 10.3390/jof6010012

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