Article
Rampant transposition following RNAi loss causes hypermutation and antifungal drug resistance in clinical isolates of a human fungal pathogen
2021-08-20
Abstract excerpt
<title>Abstract</title> <p>Microorganisms survive and compete within their environmental niches and avoid evolutionary stagnation by stochastically acquiring mutations that enhance fitness. Although increased mutation rates are often deleterious in multicellular organisms, hypermutation can be beneficial for microbes in the context of strong selective pressures. To explore how hypermutation arises in nature and e...
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Identifiers and source
- Literature Corpus work
- 76f5c508-d18d-52d2-824e-d0a5a8f925fa
- DOI
- 10.21203/rs.3.rs-804218/v1