Article

Mapping the NFYA 3′UTR landscape identifies alternative polyadenylation as a targetable vulnerability in prostate cancer

2026-05-27

Abstract excerpt

<title>Abstract</title> <p> Background Alternative polyadenylation (APA) is increasingly recognized as a pervasive oncogenic mechanism that reshapes post-transcriptional gene regulation and promotes tumor aggressiveness. Whether APA contributes to the dysregulation of <italic>NFYA</italic> —encoding the regulatory subunit of the oncogenic transcription factor NF-Y—in prostate cancer (PCa) remains largely unch...

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Literature Corpus work: 29d99939-f6cd-5389-b8b8-6f0ab5be12bb
DOI: 10.21203/rs.3.rs-9733213/v1

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