Article

eRNA profiling uncovers the enhancer landscape of oesophageal adenocarcinoma and reveals new deregulated pathways

2022-05-11

Abstract excerpt

Cancer is driven by both genetic and epigenetic changes that impact on gene expression profiles and the resulting tumourigenic phenotype. Enhancers are transcriptional regulatory elements that are key to our understanding of how this rewiring of gene expression is achieved in cancer cells. Here we have harnessed the power of RNA-seq data from hundreds of patients with oesophageal adenocarcinoma (OAC) or its precur...

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Literature Corpus work: 29d31efb-9e19-5f0d-ab54-81ee5d5a9c2c
DOI: 10.1101/2022.05.11.491502

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