Article

Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to Oesophageal Adenocarcinoma

2020-02-11

Abstract excerpt

Oesophageal adenocarcinoma (OAC) is one of the most common causes of cancer deaths and yet compared to other common cancers, we know relatively little about the underlying molecular mechanisms. Barrett’s oesophagus (BO) is the only known precancerous precursor to OAC, but our understanding about the specific events leading to OAC development is limited. Here, we have integrated gene expression and chromatin access...

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Literature Corpus work: 1a6e97af-5bf8-5432-921d-c0f79fd33515
DOI: 10.1101/2020.02.10.941872

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Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to Oesophageal AdenocarcinomaDOI 10.1101/2020.02.10.941872Read

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