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Article

The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes

9 Jun 2023

Abstract excerpt

Abstract Most cancer types exhibit aberrant transcriptional activity, including derepression of retrotransposable elements (RTEs). However, the degree, specificity and potential consequences of RTE transcriptional activation may differ substantially among cancer types and subtypes. Representing one extreme of the spectrum, we characterize the transcriptional activity of RTEs in cohorts of esophageal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37502711
DOI: 10.1093/narcan/zcad040

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