Article
Novel Aberrations Uncovered in Barrett's Esophagus and Esophageal Adenocarcinoma Using Whole Transcriptome Sequencing.
Molecular cancer research : MCR - 1 Nov 2017
Maag Jesper L V, Fisher Oliver M, Levert-Mignon Angelique, Kaczorowski Dominik C, Thomas Melissa L, Hussey Damian J, Watson David I, Wettstein Antony, Bobryshev Yuri V, Edwards Melanie, Dinger Marcel E, Lord Reginald V
Abstract excerpt
Esophageal adenocarcinoma (EAC) has one of the fastest increases in incidence of any cancer, along with poor five-year survival rates. Barrett's esophagus (BE) is the main risk factor for EAC; however, the mechanisms driving EAC development remain poorly understood. Here, transcriptomic profiling was performed using RNA-sequencing (RNA-seq) on premalignant and malignant Barrett's tissues to better understand this...
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