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Polygenic Risk Scores for Prediction of Breast Cancer in Korean women

2021-11-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Polygenic risk scores (PRSs) developed using European and Asian GWAS have been shown to have good discrimination in Asian women. However, prospective calibration of absolute risk prediction models based on a PRS or PRS combined with lifestyle clinical and environmental factors in Asian women is limited. We evaluate the discrimination and calibration of several breast cancer PR...

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Literature Corpus work
fded5487-60bd-5505-b6e5-e32b16698085
DOI
10.1101/2021.11.18.21266495
Open publication

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Polygenic Risk Scores for Prediction of Breast Cancer in Korean womenDOI 10.1101/2021.11.18.21266495
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