Article
Adaptation to ER Stress by Slt2, Counterpart of Human MAP Kinase ERK1/2, via Enhancing Splicing and Translation of <i>HAC1</i> mRNA in <i>Saccharomyces cerevisiae</i>
2023-11-19
Abstract excerpt
Unfolded protein response (UPR) is a cellular strategy to increase the protein folding capacity of cells in response to stress within the endoplasmic reticulum (ER). In metazoan cells, three major UPR sensors Ire1, PERK and ATF6 work in concert by simultaneously activating intracellular signaling pathways and modulating a series of physiological processes such as attenuation of the general protein synthesis and ex...
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Identifiers and source
- Literature Corpus work
- 2911485e-257e-5a84-837b-2bc8f5a5df83
- DOI
- 10.1101/2023.11.19.567283
