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Article

Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway.

The EMBO journal - 1 Jun 1999

Gonzalez T N, Sidrauski C, Dörfler S, Walter P

Abstract excerpt

The unfolded protein response is an intracellular signaling pathway that, in response to accumulation of misfolded proteins in the lumen of the endoplasmic reticulum (ER), upregulates transcription of ER resident chaperones. A key step in this pathway is the non-conventional, regulated splicing of the mRNA encoding the positive transcriptional regulator Hac1p. In the yeast Saccharomyces cerevisiae, the...

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Identifiers

PMID: 10357823
DOI: 10.1093/emboj/18.11.3119
PMCID: PMC1171393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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