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Intestinal epithelial Axin1 deficiency protects against colitis via altered gut microbiota

2022-03-26

Abstract excerpt

<h4>Background and Aims</h4> Intestinal homeostasis is maintained by specialized host cells and the gut microbiota. Wnt/β-catenin signaling is essential for gastrointestinal development and homeostasis, and its dysregulation has been implicated in inflammation and colorectal cancer. Axin1 negatively regulates activated Wnt/β-catenin signaling, but little is known regarding its role in regulating host-microbial in...

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Literature Corpus work
288fae96-d51d-5b9f-8cc5-15920dcbae2e
DOI
10.1101/2022.03.23.485334
Open publication

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Intestinal epithelial Axin1 deficiency protects against colitis via altered gut microbiotaDOI 10.1101/2022.03.23.485334
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