Article

Controlled and orthogonal partitioning of large particles into biomolecular condensates

2024-07-16

Abstract excerpt

Biomolecular condensates arising from liquid-liquid phase separation contribute to diverse cellular processes, such as gene expression. Partitioning of client molecules into condensates is critical to regulating the composition and function of condensates. Previous studies suggest that client size limits partitioning, with dextrans >5 nm excluded from condensates. Here, we asked whether larger particles, such as m...

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Literature Corpus work: 0b79532e-9a48-5deb-87e1-4d1386be5861
DOI: 10.1101/2024.07.11.603072

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