Article

Compositional control of FUS condensate ageing through aggregation-prone interaction networks

2026-08-02

Abstract excerpt

Stress granules are multicomponent biomolecular condensates whose aberrant ageing has been implicated in numerous neurodegenerative diseases. Although their composition is known to influence condensate properties, the molecular principles linking composition to structural maturation remain poorly understood. Here, we perform equilibrium and non-equilibrium residue-resolution molecular dynamics simulations to deter...

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Literature Corpus work: 71594d3c-7b50-5f05-af04-d5e70179c565
DOI: 10.64898/2026.07.31.741205

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