Article

The guardian of the genome meets a viral master gene regulator at a biomolecular condensate

2022-02-10

Abstract excerpt

<h4>ABSTRACT</h4> As guardian of the genome, p53 exerts its tumor suppressor activity by modulating the expression of several hundreds of genes and by interacting with a large number of proteins. However, p53 can also repress viral replication and it is targeted by a variety of viral proteins to allow viral replication to proceed. p53 can repress human papillomavirus replication by binding to the viral E2 master...

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Literature Corpus work: 25e290e0-8dc3-50f6-8e92-e48937ab5f3e
DOI: 10.1101/2022.02.09.479752

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