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Virus-induced paraspeckle-like condensates are essential hubs for gene expression and their formation drives genomic instability

2024-07-23

Abstract excerpt

<h4>Summary</h4> The nucleus is a highly structured environment containing multiple membrane-less bodies formed through liquid-liquid phase separation. These provide spatial separation and concentration of specific biomolecules enabling efficient and discrete processes to occur which regulate gene expression. One such nuclear body, paraspeckles, are comprised of multiple paraspeckle proteins (PSPs) built around t...

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Literature Corpus work
86e47a48-a42a-577d-beb4-a34311601204
DOI
10.1101/2024.07.23.604779
Open publication

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Virus-induced paraspeckle-like condensates are essential hubs for gene expression and their formation drives genomic instabilityDOI 10.1101/2024.07.23.604779
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