Article

Type 2 Diabetes Risk Prediction Incorporating Family History Revealing a Substantial Fraction of Missing Heritability

2016-02-25

Abstract excerpt

<h4>ABSTRACT</h4> Despite many successes of genome-wide association (GWA) studies, known susceptibility variants identified by GWAS have the modest effect sizes and we met noticeable skepticism about the risk prediction model building with large-scale genetic data. However, in contrast with genetic variants, family history of diseases has been largely accepted as an important risk factor in clinical diagnosis and...

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Literature Corpus work: 25b6174c-7a4d-5070-98e9-5826a0dce0e2
DOI: 10.1101/041335

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