Article

Combining case-control status and family history of disease increases association power

2019-08-02

Abstract excerpt

Family history of disease can provide valuable information about an individual’s genetic liability for disease in case-control association studies, but it is currently unclear how to best combine case-control status and family history of disease. We developed a new association method based on posterior mean genetic liabilities under a liability threshold model, conditional on both case-control status and family hi...

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Identifiers and source

Literature Corpus work: 1418148f-50a5-5e75-9cfa-0fd975465976
DOI: 10.1101/722645

Open publication

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