Article

Early Postnatal Dysfunction of ACC PV Interneurons in Shank3B <sup>-/-</sup> Mice

2024-10-04

Abstract excerpt

Anterior cingulate cortex (ACC) dysfunction is implicated in the cognitive and social deficits associated with autism spectrum disorder (ASD) , yet the developmental trajectory of ACC circuit maturation in ASD remains poorly understood. Here, we examined the postnatal development of glutamatergic synaptic connectivity and intrinsic excitability in layer 2/3 pyramidal neurons (PYR) and Parvalbumin-expressing int...

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Literature Corpus work: 25825c89-5ac2-5fcd-8537-087bf085fe70
DOI: 10.1101/2024.10.04.616584

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