Article

Developmental dysregulation of chandelier cell excitability in a mouse model of Dravet Syndrome

2026-02-02

Abstract excerpt

<h4>ABSTRACT</h4> Chandelier cells (ChCs) are a rare and highly specialized sub-type of inhibitory neuron in the cerebral cortex that specifically and exclusively form synapses onto the axon initial segment of excitatory neurons and thereby exert powerful control of excitability. We applied a newly developed, cell type-specific enhancer element to label ChCs and assess their electrophysiological and morphological...

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Literature Corpus work: ee07a901-eaea-5dce-b09b-ff0a8f8e04a6
DOI: 10.64898/2026.02.02.702918

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