Article

Challenging the gold standard: critical limitations in clinical detection of drug-resistant tuberculosis

2023-03-01

Abstract excerpt

Heteroresistant infections - defined as infections in which minority drug-resistant (DR) populations are present - are a challenge in infectious disease control. In Mycobacterium tuberculosis , heteroresistance poses challenges in diagnosis and has been linked with poor treatment outcomes. We compared the analytic sensitivity of molecular methods, such as GeneXpert and whole genome sequencing (WGS) in detecting he...

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Literature Corpus work: 257a9b3c-30ee-5b7b-8a6f-042cdb27487a
DOI: 10.1101/2023.02.27.23286518

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