Article

Efficient CRISPR/Cas9 mutagenesis for neurobehavioral screening in adult zebrafish

2021-02-02

Abstract excerpt

<h4>ABSTRACT</h4> Adult zebrafish are increasingly used to interrogate mechanisms of disease development and tissue regeneration. Yet, the prospect of large-scale genetics in adult zebrafish has traditionally faced a host of biological and technical challenges. Here, we describe an experimental pipeline that combines high-efficiency CRISPR/Cas9 mutagenesis with functional phenotypic screening to identify genes re...

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Literature Corpus work: 25784dde-6b67-5fe7-8368-18b63364297e
DOI: 10.1101/2021.02.01.429280

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