Article

Colocalization of GWAS and eQTL Signals Detects Target Genes

2016-07-21

Abstract excerpt

The vast majority of genome-wide association studies (GWAS) risk loci fall in non-coding regions of the genome. One possible hypothesis is that these GWAS risk loci alter the individual’s disease risk through their effect on gene expression in different tissues. In order to understand the mechanisms driving a GWAS risk locus, it is helpful to determine which gene is affected in specific tissue types. For example,...

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Literature Corpus work: 88128ba9-fd0b-53ed-bf0d-6717bdd3a886
DOI: 10.1101/065037

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