Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

Abstract excerpt

Genetic association studies, in particular the genome-wide association study (GWAS) design, have provided a wealth of novel insights into the aetiology of a wide range of human diseases and traits, in particular cardiovascular diseases and lipid biomarkers. The next challenge consists of understanding the molecular basis of these associations. The integration of multiple association datasets, including gene...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Associations and Epidemiology
• Share to Lipid metabolism and disorders
• Share to Liver Disease Diagnosis and Treatment