Article

Probabilistic Colocalization of Genetic Variants from Complex and Molecular Traits: Promise and Limitations

2020-07-01

Abstract excerpt

Colocalization analysis has emerged as a powerful tool to uncover the overlapping of causal variants responsible for both molecular and complex disease phenotypes. The findings from colocalization analysis yield insights into the molecular pathways of complex diseases. In this paper, we conduct an in-depth investigation of the promise and limitations of the available colocalization analysis approaches. Focusing on...

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Literature Corpus work: 71403fdf-742e-5915-938f-21f22f902e95
DOI: 10.1101/2020.07.01.182097

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