Article

Polygenic risk scores based on European GWAS correlate to disease prevalence differences around the world

2021-11-14

Abstract excerpt

<h4>Background</h4> Complex disorders are caused by a combination of genetic, environmental and lifestyle factors, and their prevalence can vary greatly across different populations. Genome wide association studies (GWAS) can help identify common variants that underlie disease risk. However, despite their increasing number, the vast majority of studies focuses on European populations, leading to questions regardin...

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Literature Corpus work: 4035a2ac-ea38-5199-884a-b9441c0dfb02
DOI: 10.1101/2021.11.13.21265898

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