Article

Reconstructing phylogenies of metastatic cancers

2016-04-11

Abstract excerpt

Reconstructing the evolutionary history of metastases is critical for understanding their basic biological principles and has profound clinical implications 1–3 . Genome-wide sequencing data has enabled modern phylogenomic methods to accurately dissect subclones and their phylogenies from noisy and impure bulk tumor samples at unprecedented depth 4–7 . However, existing methods are not designed to infer metastat...

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Literature Corpus work: 24c71d9a-a369-54fb-ab81-0221cbb144dd
DOI: 10.1101/048157

Open publication

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