Article

MSIsensor-RNA: Microsatellite Instability Detection for Bulk and Single-cell Gene Expression Data

2023-10-12

Abstract excerpt

Microsatellite instability (MSI) is an indispensable biomarker in cancer immunotherapy. Currently, MSI scoring methods by high-throughput omics methods have gained popularity and demonstrated better performance than the gold standard method for MSI detection. However, the MSI detection method on expression data, especially single-cell expression data, is still lacking, limiting the scope of clinical application an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 246b8eab-ce8b-5f9e-846c-49b1e39738b0
DOI: 10.1101/2023.10.09.561613

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MSIsensor-RNA: Microsatellite Instability Detection for Bulk and Single-cell Gene Expression DataDOI 10.1101/2023.10.09.561613Read

MSIsensor-RNA: Microsatellite Instability Detection for Bulk and Single-cell Gene Expression DataSemantic proximity Read

PreMSIm: An R package for predicting microsatellite instability from the expression profiling of a gene panel in cancerSemantic proximity Read

Performance assessment of computational tools to detect microsatellite instabilitySemantic proximity Read

A molecular portrait of microsatellite instability across multiple cancers.Semantic proximity Read

A molecular portrait of microsatellite instability across multiple cancersSemantic proximity Read

Analysis of Microsatellite Instability Intensity in Single-Cell Resolution with scMnT reveals Tumor Heterogeneity in Colorectal CancerSemantic proximity Read

MSICKB: A Curated Knowledgebase for Exploring Molecular Heterogeneity and Biomarker Discovery in Microsatellite Instability CancersSemantic proximity Read

Classification and characterization of microsatellite instability across 18 cancer types.Semantic proximity Read

Multi-omics characterization and validation of MSI-related molecular features across multiple malignancies.Semantic proximity Read

Machine Learning Algorithm for the Detection of Tumor Microsatellite Instability Based on Multiomics Biomarkers.Semantic proximity Read

Performance evaluation for rapid detection of pan-cancer microsatellite instability with MANTIS.Semantic proximity Read

A Novel Next-Generation Sequencing Approach to Detecting Microsatellite Instability and Pan-Tumor Characterization of 1000 Microsatellite Instability–High Cases in 67,000 Patient SamplesSemantic proximity Read