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Article

Performance evaluation for rapid detection of pan-cancer microsatellite instability with MANTIS.

Oncotarget - 31 Jan 2017

Kautto Esko A, Bonneville Russell, Miya Jharna, Yu Lianbo, Krook Melanie A, Reeser Julie W, Roychowdhury Sameek

Abstract excerpt

In current clinical practice, microsatellite instability (MSI) and mismatch repair deficiency detection is performed with MSI-PCR and immunohistochemistry. Recent research has produced several computational tools for MSI detection with next-generation sequencing (NGS) data; however a comprehensive analysis of computational methods has not yet been performed. In this study, we introduce a new MSI detection tool,...

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Identifiers

PMID: 27980218
DOI: 10.18632/oncotarget.13918
PMCID: PMC5352334

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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