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Performance assessment of computational tools to detect microsatellite instability

25 Jul 2024

Abstract excerpt

Microsatellite instability (MSI) is a phenomenon seen in several cancer types, which can be used as a biomarker to help guide immune checkpoint inhibitor treatment. To facilitate this, researchers have developed computational tools to categorize samples as having high microsatellite instability, or as being microsatellite stable using next-generation sequencing data. Most of these tools were published with...

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PMID: 39129364
DOI: 10.1093/bib/bbae390

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