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PreMSIm: An R package for predicting microsatellite instability from the expression profiling of a gene panel in cancer

1 Jan 2020

Abstract excerpt

Microsatellite instability (MSI) is a genomic property of the cancers with defective DNA mismatch repair and is a useful marker for cancer diagnosis and treatment in diverse cancer types. In particular, MSI has been associated with the active immune checkpoint blockade therapy response in cancer. Most of computational methods for predicting MSI are based on DNA sequencing data and a few are based on mRNA...

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PMID: 32257050
DOI: 10.1016/j.csbj.2020.03.007

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