Article

Human effector CD8 <sup>+</sup> T cells with an exhausted-like phenotype control tumor growth <i>in vivo</i> in a humanized tumor model

2023-10-14

Abstract excerpt

<h4>Background</h4> Humanized tumor models could be particularly valuable for cancer immunotherapy research, as they may better reflect human-specific aspects of the interfaces between tumor and immune system of human cancer. However, endogenous antitumor immunity in humanized models is still largely undefined. <h4>Methods</h4> We established a novel autologous humanized mouse tumor model by using NSG mice recon...

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Literature Corpus work: 24132f62-d624-51e8-ab4b-2470bb4b0495
DOI: 10.1101/2023.10.11.561856

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