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Inhibition of the Notch signal transducer CSL by Pkc53E-mediated phosphorylation to fend off parasitic immune challenge in <i>Drosophila</i>

2023-06-17

Abstract excerpt

Notch signalling activity regulates hematopoiesis in Drosophila and vertebrates alike. Parasitoid wasp infestation of Drosophila larvae, however, requires a timely downregulation of Notch activity to allow the formation of encapsulation-active blood cells. Here we show that the Drosophila CSL transcription factor Suppressor of Hairless [Su(H)] is phosphorylated at Serine 269 in response to parasitoid wasp infes...

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Literature Corpus work
22ed94a5-9ffe-5001-9457-083aff26007b
DOI
10.1101/2023.06.16.545247
Open publication

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Inhibition of the Notch signal transducer CSL by Pkc53E-mediated phosphorylation to fend off parasitic immune challenge in <i>Drosophila</i>DOI 10.1101/2023.06.16.545247
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