Article
Mutation of potential MAPK phosphorylation sites in the Notch antagonist Hairless.
Hereditas - 1 Oct 2014
Nagel Anja C, Preiss Anette
Abstract excerpt
Cellular differentiation during eumetazoan development is based on highly conserved signalling pathways. Two of them, the Notch and the EGFR signalling pathways, are closely intertwined. We have identified two potential target sites of the Mitogen activated kinase (MAPK), the downstream effector kinase of EGFR, within Hairless (H), the major antagonist of Notch signalling in Drosophila. Assuming that...
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