Article

EpCAM sustains crypt mechanics and prevents aberrant remodeling

2026-04-30

Abstract excerpt

<h4>SUMMARY</h4> Crypt morphogenesis is a fundamental process that drives intestinal growth and maintains its homeostasis. Although intestinal tissue mechanics is recognized as pivotal for early crypt initiation and budding, the molecular mechanisms that couple epithelial forces to mature crypt behavior remain largely unexplored. In particular, while Paneth cells have been proposed to be implicated in the mechani...

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Literature Corpus work: 21a2ab4d-9907-518a-a549-18fc75ed916b
DOI: 10.64898/2026.04.27.721034

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