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Physical organogenesis of the gut

15 Aug 2022

Abstract excerpt

The gut has been a central subject of organogenesis since Caspar Friedrich Wolff's seminal 1769 work 'De Formatione Intestinorum'. Today, we are moving from a purely genetic understanding of cell specification to a model in which genetics codes for layers of physical-mechanical and electrical properties that drive organogenesis such that organ function and morphogenesis are deeply intertwined. This Review...

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PMID: 35980364
DOI: 10.1242/dev.200765

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