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Article

Functional consequences of EpCam mutation in mice and men.

American journal of physiology. Gastrointestinal and liver physiology - 15 Feb 2014

Mueller James L, McGeough Matthew D, Peña Carla A, Sivagnanam Mamata

Abstract excerpt

Congenital tufting enteropathy (CTE) is a severe diarrheal disease of infancy characterized by villous changes and epithelial tufts. We previously identified mutations in epithelial cell adhesion molecule (EpCAM) as the cause of CTE. We developed an in vivo mouse model of CTE based on EpCAM mutations found in patients with the aim to further elucidate the in vivo role of EpCAM and allow for a direct comparison to...

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Share to Antigens, Neoplasm
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24337010
DOI: 10.1152/ajpgi.00286.2013
PMCID: PMC3920125

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Functional consequences of EpCam mutation in mice and men.PMID 24337010Read ↗

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