Article
Live and let die in the intestinal epithelium.
Current opinion in cell biology - 1 Dec 2003
Sancho Elena, Batlle Eduard, Clevers Hans
Abstract excerpt
The intestinal epithelium is a relatively simple developmental system and a prime example of tissue renewal from a source of multipotent stem cells. Throughout adulthood, intestinal epithelial proliferation, cell-fate specification and differentiation are coupled to migration in discrete units known as crypts of Lieberkühn. Physically guided by Eph receptors and their ligands, the ephrins, stem cell progeny...
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