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Time-restricted feeding exacerbates liver fibrosis by promoting BDH1-mediated ketolysis in hepatic stellate cells

2026-03-24

Abstract excerpt

Time-restricted feeding (TRF) is widely considered metabolically beneficial, yet its impact on chronic liver disease progression remains poorly defined. This study investigates the effects of TRF on liver fibrogenesis. Using carbon tetrachloride (CCl 4 )-induced, bile duct ligation (BDL)-induced, and choline-deficient, L-amino acid-defined high-fat diet (CDAHFD)-induced murine models of liver fibrosis, we demonst...

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Identifiers and source

Literature Corpus work
2106c713-c391-5e9b-a7e2-e3ad2ad3d73f
DOI
10.64898/2026.03.21.712927
Open publication

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Time-restricted feeding exacerbates liver fibrosis by promoting BDH1-mediated ketolysis in hepatic stellate cellsDOI 10.64898/2026.03.21.712927
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