An 8-Week Very Low-Calorie Ketogenic Diet (VLCKD) Alters the Landscape of Obese-Derived Small Extracellular Vesicles (sEVs), Redefining Hepatic Cell Phenotypes.

doi:10.3390/nu16234189

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

An 8-Week Very Low-Calorie Ketogenic Diet (VLCKD) Alters the Landscape of Obese-Derived Small Extracellular Vesicles (sEVs), Redefining Hepatic Cell Phenotypes.

Nutrients - 4 Dec 2024

Balestra Francesco, De Luca Maria, Panzetta Giorgia, Depalo Nicoletta, Rizzi Federica, Mastrogiacomo Rita, Coletta Sergio, Serino Grazia, Piccinno Emanuele, Stabile Dolores, Pesole Pasqua Letizia, De Nunzio Valentina, Pinto Giuliano, Cerabino Nicole, Di Chito Martina, Notarnicola Maria, Shahini Endrit, De Pergola Giovanni, Scavo Maria Principia

Abstract excerpt

Background. Very low-calorie ketogenic diets (VLCKD) are an effective weight-loss strategy for obese individuals, reducing risks of liver conditions such as non-alcoholic steatohepatitis and fibrosis. Small extracellular vesicles (sEVs) are implicated in liver fibrosis by influencing hepatic cell phenotypes and contributing to liver damage. This study investigates sEVs derived from serum of 60 obese adults...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caloric Restriction

Share to Diet, Ketogenic

Share to Extracellular Vesicles

Share to Hepatocytes

Share to Liver

Share to Liver Cirrhosis

Share to Obesity

Source

Open in PubMed Open full text

Identifiers

PMID: 39683581
DOI: 10.3390/nu16234189
PMCID: PMC11643994

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An 8-Week Very Low-Calorie Ketogenic Diet (VLCKD) Alters the Landscape of Obese-Derived Small Extracellular Vesicles (sEVs), Redefining Hepatic Cell Phenotypes.PMID 39683581Read ↗

Exploring Organ-Specific Extracellular Vesicles in Metabolic Improvements Following Bariatric Surgery in Adolescents with ObesitySemantic proximity Read ↗

Global molecular landscape of early MASLD progression in obesitySemantic proximity Read ↗

The hepatocellular model of fatty liver disease: from current imaging diagnostics to innovative proteomics technologiesSemantic proximity Read ↗

From Carbohydrates to Ketones: Mitochondrial Reprogramming via β-Hydroxybutyrate Signaling for Non-Pharmacological Treatment of Metabolic SyndromeSemantic proximity Read ↗

Found in translation—Fibrosis in metabolic dysfunction–associated steatohepatitis (MASH)Semantic proximity Read ↗

Inter-Organ Crosstalk in MASLD: A Narrative ReviewSemantic proximity Read ↗

Multiomics analyses decipher intricate changes in the cellular and metabolic landscape of steatotic livers upon dietary restriction and sleeve gastrectomySemantic proximity Read ↗

Recapitulation of clinical and molecular hallmarks of lipid-induced hepatic insulin resistance in a zonated, vascularized human liver acinus microphysiological system during metabolic dysfunction-associated steatotic liver disease (MASLD) progressionSemantic proximity Read ↗

Extracellular Vesicles as Biomarkers for Steatosis Stages in MASLD Patients: an Algorithmic Approach Using Explainable Artificial IntelligenceSemantic proximity Read ↗

Exosomes Derived from Human Adipose Mesenchymal Stem Cells Ameliorate Hepatic Fibrosis by Regulating Choline Metabolism and PI3K/Akt/mTOR PathwaySemantic proximity Read ↗

Extracellular Vesicles as Biomarkers for Steatosis Stages in MASLD Patients: an Algorithmic Approach Using Explainable Artificial IntelligenceSemantic proximity Read ↗

Extracellular Vesicles as Biomarkers in Liver DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.