Article
Ketone body metabolism declines with age in mice in a sex-dependent manner
2022-10-07
Abstract excerpt
Understanding how our cells maintain energy homeostasis has long been a focus of aging biology. A decline in energy metabolism is central to many age-related diseases such as Alzheimer’s disease, heart failure, frailty, and delirium. Intervening on pathways involved in energy homeostasis can extend healthy lifespan. When the primary energy substrate glucose is scarce, mice and humans can partially switch cellular...
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Identifiers and source
- Literature Corpus work
- 1bfd2576-2bb0-56c2-9b6e-41fcf8d55fcb
- DOI
- 10.1101/2022.10.05.511032