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Article

DEVELOPMENT OF ORGANOID BASED MODEL TO STUDY IMMUNE-NEURAL INTERACTIONS IN HUMAN CNS DISEASES

2026-08-17

Abstract excerpt

<h4>ABSTRACT</h4> Modeling neural-immune interactions in neurodegenerative and immune-mediated central nervous system (CNS) diseases requires human 3D models that capture cellular diversity and long-term tissue maturation. Here, we present an enhanced human induced pluripotent stem cell (hiPSC)-derived cerebral organoid (CO) platform optimized to mitigate core hypoxia for over 200 days. Timed pro-myelinating cues...

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Literature Corpus work
209ed861-cd5e-5422-8fe3-d68102140336
DOI
10.64898/2026.08.14.26360461
Open publication

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