Article

Generation of star-shaped human induced astrocytes with a mature inflammatory phenotype for CNS disease modeling

2021-06-07

Abstract excerpt

<h4>Summary</h4> Generating astrocytes from induced pluripotent stem cells has been hampered by either prolonged differentiation -spanning over two months -or by shorter protocols that generate immature astrocytes, devoid of salient inflammation-associated astrocytic traits pivotal for CNS neuropathological modeling. We directed human neural stem cells derived from induced pluripotent stem cells to astrocytic com...

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Literature Corpus work: a90c5905-4c9a-52ac-a17e-f4f359d72f69
DOI: 10.1101/2021.06.07.447336

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