Article

Advanced human cerebral organoids as a model for investigating glioma stem cell interactions with microglia and vascular cells and response to radiotherapy

2024-11-30

Abstract excerpt

<h4>ABSTRACT</h4> The recent development of human brain organoids from induced pluripotent stem cells (IPSCs) enables the modeling of brain biology and pathophysiology, such as gliomas. However, most models lack vascular and/or immune systems, both of which play essential roles in maintaining brain health and in pathophysiological mechanisms. We have established a new method for generating vascularized complex ce...

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Literature Corpus work: f9a34430-a345-5df1-bbf8-9a3cf40ecc10
DOI: 10.1101/2024.11.28.625826

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