Article
A Cross-scale Causal Mapping Framework Pinpoints Macrophage Orchestrators of Balanced Arterial Development
2025-10-09
Abstract excerpt
Postnatal pulmonary arteries experience an abrupt surge in flow that demands tightly coordinated remodeling of vascular structure and mechanical compliance. However, the cellular programs orchestrating these multiscale adaptation remain poorly defined, partly due to the absence of analytical tools integrating gene–cell–tissue scales. Here, we present CausaLink, a cross-scale causal mapping framework that predicts...
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Identifiers and source
- Literature Corpus work
- 2072b86a-9d7b-5442-aae4-ceca8ba03219
- DOI
- 10.1101/2025.10.08.681286