Article

A Transcriptional Atlas of Endothelial Cell Zonation Along the Pulmonary Vascular Tree

2025-05-19

Abstract excerpt

<h4>Background</h4> The lung vasculature is comprised of a series of branching vessels extending from the main pulmonary artery to the alveolar capillaries, then back to the pulmonary veins. Lung endothelial cells (EC) exist along this continuum, exposed to gradients of shear stress, oxygen tension and pressure. Single cell RNA sequencing (scRNA-seq) has identified lung EC subsets, but many aspects of the vascula...

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Literature Corpus work: 41a7db80-18d4-5c3b-b6c2-6ce40f8c612c
DOI: 10.1101/2025.05.17.654540

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