Article

Chromatin and gene-regulatory dynamics of human pulmogenesis by single cell multiomic sequencing

2025-09-25

Abstract excerpt

Human lung development is governed by complex gene regulatory networks that orchestrate cellular differentiation and organogenesis. We present a single cell multiomic atlas of human pulmogenesis, simultaneously capturing both the chromatin accessibility profile and the transcriptome from each cell across fetal lungs spanning from post-conception weeks (PCW) 12 to 23. We identified 44 distinct developing cell clust...

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Literature Corpus work: 5bceef26-9c13-5836-97e4-5a87c3674eac
DOI: 10.1101/2025.09.24.678382

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