Back to search

Article

Evaluation of the causal effects of blood lipid levels on gout with summary level GWAS data: two-sample Mendelian randomization and mediation analysis

2019-09-16

Abstract excerpt

<h4>Objective</h4> Many observational studies have identified that gout patients are often comorbid with dyslipidemia, which is typically characterized by a decrease in high-density lipoprotein cholesterol (HDL) and an increase in triglycerides (TG). However, the relationship between dyslipidemia and gout is still unclear. <h4>Methods</h4> We first performed a two-sample Mendelian randomization (MR) to evaluate th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
202b5faa-0340-591d-980a-5d5be2c7be03
DOI
10.1101/19006296
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Evaluation of the causal effects of blood lipid levels on gout with summary level GWAS data: two-sample Mendelian randomization and mediation analysisDOI 10.1101/19006296
Select a neighboring publication to make it the new centre.